Intro
This guide will grade longevity interventions by the quality of evidence and the magnitude of plausible benefit.
Key Points
- “Longevity” often means disease prevention + functional maintenance
- Evidence is strongest for: exercise, BP control, smoking cessation, vaccines, metabolic risk control
- Supplements and “biohacks” often have weaker human evidence
Evidence buckets (stub)
- Strong: exercise, BP control, smoking cessation
- Moderate: sleep optimization, diet quality patterns
- Unclear/experimental: many supplements, off-label longevity drugs
FAQ
Q: What has the best evidence for healthspan?
A: Foundational prevention: exercise, BP control, smoking cessation, vaccines, metabolic risk reduction.
Q: Do supplements extend lifespan?
A: Usually limited evidence in humans; benefits often relate to deficiencies.