Aging & Longevity
Guides and analysis on aging biology, lifespan heritability, and the difference between intrinsic and extrinsic mortality.
Aging research is shifting from treating diseases individually to understanding the shared biological processes that increase vulnerability over time. This hub organizes those concepts — from mortality theory to molecular mechanisms.
🧭 Start Here — Foundations
If you're new to longevity science, begin with these core concepts.
- Intrinsic vs Extrinsic Mortality
The key distinction that clarifies most debates about aging, genetics, and longevity.
- Healthspan vs Lifespan
Why living longer and living well aren't the same thing.
- Biological Age vs Chronological Age
How your body's age can diverge from the calendar — and why it matters.
🧬 Mechanisms
How aging actually happens at the biological level.
- The Hallmarks of Aging Explained
The core biological processes that drive aging — and how they shape healthspan, lifespan, and disease risk.
📰 Analysis & Debate
Where longevity science challenges conventional thinking.
- Longevity Genetics Just Got Rehabilitated
New evidence suggesting intrinsic human lifespan may be ~50–55% heritable once confounding deaths are removed.
- How "Lifestyle Over Genes" Became Medical Dogma
Why aging genetics were sidelined — and why that story is now collapsing.
🆕 Latest additions
🔭 What's Coming Next
Planned and in development:
- Aging & Longevity Basics
- Longevity Interventions: What Has Evidence?
- Epigenetics and Aging
- GLP-1 Drugs and Aging
In progress (drafts)
These posts already exist in the repository but are not yet published. Titles and structure may still change.
- Longevity Genetics Just Got Rehabilitated Post · Draft
- How "Lifestyle Over Genes" Became Medical Dogma Post · Draft