Anaphylaxis — Severe Allergic Reaction

How to recognize and respond to severe allergic reactions (anaphylaxis) with epinephrine and emergency action.

Intro

Food and environmental allergies are common, but anaphylaxis is a severe, life-threatening allergic reaction. It can happen within minutes of exposure to an allergen, and requires immediate emergency action. Even a tiny exposure can trigger a reaction in sensitive individuals.

Key Points

  • Anaphylaxis is a medical emergency — use epinephrine (adrenaline) immediately.
  • Common triggers: peanuts, tree nuts, shellfish, milk, eggs, insect stings, certain medicines.
  • Symptoms can progress quickly — from hives and swelling to breathing difficulty and collapse.
  • Always call emergency services, even after epinephrine use.
  • People at risk should carry an auto-injector and action plan at all times.

Common Allergens

  • Peanuts and tree nuts
  • Shellfish and fish
  • Milk and eggs
  • Wheat and soy
  • Sesame
  • Insect stings and some medicines (e.g., antibiotics, NSAIDs)

Symptoms

  • Mild/moderate: itching, hives, swelling of lips/face, abdominal pain, vomiting
  • Severe (anaphylaxis): difficulty breathing, wheezing, swelling of tongue/throat, dizziness, fainting, collapse

First Aid for Anaphylaxis ⚠️

  1. Use epinephrine auto-injector immediately (e.g., EpiPen).
  2. Call emergency services.
  3. Lay the person flat with legs elevated — unless breathing is very difficult (then allow sitting up).
  4. If no improvement after 5–10 minutes, give a second dose if available.
  5. Monitor breathing and circulation — be prepared to start CPR if necessary.

Prevention

  • Read food and medicine labels carefully.
  • Avoid cross-contamination when preparing food.
  • Inform restaurants, schools, and workplaces about allergies.
  • Carry an action plan and wear medical alert jewellery.

FAQ

Q: Why use epinephrine first and not antihistamines?
A: Epinephrine is the only life-saving treatment for anaphylaxis. Antihistamines may help mild symptoms (like hives) but do not stop airway or circulation collapse.

Q: Do I still need to go to the hospital if symptoms improve?
A: Yes. A reaction can return (biphasic reaction), so medical monitoring is essential.

Q: Can children outgrow food allergies?
A: Some do (e.g., milk or egg), but others (like peanut and tree nut) often persist. Always follow up with an allergy specialist.

Further Reading


References

Simons, F.E.R., et al. (2020). World Allergy Organization anaphylaxis guidance 2020. World Allergy Organization Journal, 13(10), 100472.


⚠️ Educational only; not a substitute for professional medical advice. Always call emergency services immediately if anaphylaxis is suspected.