Thought Archive

Diabetes

DKA Quick Reference (Type 1 Diabetes)

30 Aug 2025

DKA Quick Reference (Type 1 Diabetes)

Intro

Diabetic ketoacidosis (DKA) is a medical emergency caused by insufficient insulin leading to high blood glucose and acidic blood. It develops over hours and needs urgent hospital treatment.

Key Points

  • Think DKA if high glucose + positive ketones + symptoms (nausea/vomiting, abdominal pain, deep breathing, dehydration).
  • Do not delay: give correction insulin, drink fluids, and seek urgent care if ketones remain high or you’re vomiting.
  • Pump users: suspect site/tubing failure first.

Red Flags — Go to ED Now

  • Blood ketones ≥3.0 mmol/L (or moderate/large urine ketones).
  • Persistent vomiting, severe abdominal pain, drowsiness/confusion, fast/deep breathing (Kussmaul), fruity breath, or unable to keep fluids down.
  • Child, pregnancy, or significant illness → lower threshold to attend ED.

Home Assessment (If Not Yet in Distress)

  1. Check glucose and blood ketones (preferred) or urine ketones.
  2. Hydrate: small frequent sips of water/electrolytes.
  3. Inspect pump (if using): check site, tubing, occlusions; change set and give a pen/syringe correction if needed.

Quick Action Table

SituationWhat to do at home (while arranging care)
Glucose >13.9 mmol/L (>250 mg/dL) and ketones 0.6–1.4Take correction insulin per plan; drink fluids; recheck ketones in 1–2 h.
Ketones 1.5–2.9Extra insulin per sick-day plan (often 10–20% of total daily dose or 0.1 u/kg; follow your clinician’s plan); fluids; recheck hourly.
Ketones ≥3.0 or any vomiting/abdominal pain/drowsinessED now. Give correction insulin if advised, do not delay travel.

Always follow your personalized sick-day rules; numbers above are common frameworks but vary by clinic.

Common Triggers

  • Missed insulin doses or pump/site failure.
  • Infection/illness, dehydration.
  • New-onset type 1 diabetes.

In the Emergency Department — What to Expect

  • Blood tests: glucose, ketones, electrolytes, blood gases.
  • IV fluids, insulin infusion, and electrolyte (potassium) replacement.
  • Treatment of underlying cause (infection, pump failure).
  • Frequent monitoring until ketones clear and you can switch to usual insulin.

Prevention

  • Sick-day plan written and accessible.
  • Keep backup pens/syringes even if you use a pump.
  • Check ketones whenever glucose is high and you feel unwell.
  • Change infusion sets regularly; carry spares and inspect for leaks.

FAQ

Can I exercise to lower high glucose with ketones?
No. Exercise can worsen ketones when insulin is low.

I took a correction but ketones won’t drop.
Suspect pump/site failure—inject with a pen/syringe and seek care.

Does DKA happen in type 2?
Less common, but possible—especially in ketosis-prone T2 or with SGLT2 inhibitors (then called euglycaemic DKA).

Further Reading