Thought Archive

Infectious Diseases

Flu vs. Cold — Key Differences & What to Do

30 Aug 2025

Flu vs. Cold — Key Differences & What to Do

Intro

Colds and flu are both respiratory infections, but influenza tends to start suddenly, hit harder, and cause higher fever and body aches. Knowing the differences helps you decide on testing, antivirals, and when to seek care.

Key Points

  • Onset: Flu = sudden; Cold = gradual.
  • Fever & aches: Flu = higher fever & prominent body aches; Cold = milder.
  • Cough: Both can cough; flu cough often deeper and more exhausting.
  • Sore throat/runny nose: More prominent with colds.
  • Antivirals: Flu may benefit from early antivirals (within 48 hours for higher-risk groups).
  • Testing: Consider if symptoms are severe, you’re high-risk, or during known flu waves.

Symptom Comparison

FeatureFlu (Influenza)Common Cold
OnsetAbrupt (hours)Gradual (1–2 days)
FeverHigh (≥38°C / 100.4°F) commonLow-grade or none
Aches & chillsProminentMild
FatigueMarked, can be prolongedMild–moderate
HeadacheCommonLess common
Sore throatSometimesCommon
Runny/stuffy noseSometimesCommon
CoughCommon, can be severeCommon, milder

When to Test

  • Severe symptoms or high-risk (pregnancy, age ≥65, chronic heart/lung/kidney disease, diabetes, immunocompromise).
  • Outbreak exposure (household, school, workplace) during flu season.
  • If results will change management (e.g., antivirals, isolation).

Treatment

  • Flu: Rest, fluids, fever relief (paracetamol/acetaminophen or ibuprofen if appropriate).
    • Antivirals (e.g., oseltamivir) may be recommended for high-risk patients or severe disease, ideally within 48 hours of symptom onset.
  • Cold: Symptomatic care—fluids, saline nasal rinse, honey for cough (age >1), decongestants/lozenges as appropriate.

Antibiotics do not treat viral infections like flu or colds.

Red Flags — Seek Urgent Care

  • Difficulty breathing, chest pain, bluish lips/face.
  • Confusion, severe dehydration, fainting.
  • Persistent high fever (>3 days) or fever that improves then returns with worse cough.
  • In children: fast/labored breathing, lethargy, poor intake/urine, or any cyanosis.
  • In infants <3 months: any fever ≥38.0°C.

Recovery & Prevention

  • Most colds resolve in 7–10 days; flu may take 1–2 weeks (fatigue can linger).
  • Vaccination: Annual flu shot reduces risk of severe disease.
  • Reduce spread: Stay home when unwell, hand hygiene, cover coughs, consider a mask in crowded indoor spaces when symptomatic.

FAQ

How do I know it’s flu without a test?
The combination of sudden onset, high fever, and body aches during flu season strongly suggests flu, but testing is the only way to be sure.

Do I need antivirals?
If you’re at higher risk or have severe disease, speak to a clinician as soon as symptoms start—treatment works best early.

Can you have flu without a fever?
Yes, especially in older adults or those on certain medications—but it’s less common.

Further Reading